In anime, Lex is widely recognized as Suguru Geto in the smash hit Jujutsu Kaisen, but his other notable roles include Wargreymon in Digimon, Goemon in Lupin the Third, Teuchi, the Ichiraku Ramen Guy, and Hayate in Naruto, Sanosuke Sagara in Rurouni Kenshin, Jagged Stone in Miraculous Ladybug, and Goku in the Toonami Asia release of Dragonball Super.

Video game fans will recognize him as Dr. Neo Cortex in the Crash Bandicoot franchise, Kiljeaden in World of Warcraft, The Stone and Fire Trolls in God of War, Charr Male in Guild Wars, and Han Solo, Poe Dameron and Stormtroopers in Star Wars Video Games.

Lex has also made his mark in mainstream animation and TV shows, voicing several Warner Bros and DC characters, such as Batman, Dr. Doom, Captain Cold, Clayface, and Captain Atom on shows like Batman Brave and the Bold, Justice League, and Legion of Superheroes. He is also The Doorman and his dog Hundley on Curious George, Barry on The Regular Show, Major Vonreg on Star Wars Resistance, and The Candlemaker on Doom Patrol.